My computer just had a disk problem, I know this because I had to run chkdsk, and there were many errors (time for a new hard drive). Google Chrome had crashed on me while using it to fill out airline information.
After rebooting whenever Google Chrome started up, it would say:
Your profile could not be opened correctly.
Some features may be unavailable. Please check that the profile exists and you have permission to read and write its contents.
The fix (that worked for me) is easy.
This may not be the solution in all circumstances, but I just had to delete my “Web Data” file. On my computer it was located in:
After deleting my “Web Data” file, Chrome would start up again without a problem.